Anti-Saccharomyces cerevisiae IgG and IgA antibodies are associated with systemic inflammation and advanced disease in hidradenitis suppurativa

F Assan, J Gottlieb, F Tubach, S Lebbah… - Journal of Allergy and …, 2020 - jacionline.org
IgE on human basophils. Notably, the hapten dinitrophenyl incorporated into phospholipid
liposomes has been shown to induce degranulation of rat basophil leukemia cells sensitized
with dinitrophenyl-sIgE. 9 Our data expand and reinforce this earlier observation, but within
the context of glycolipid-mediated activation of primary human basophils sensitized with a
glycan-sIgE. Basophil stimulation took place in 75% RPMI media, which contains no lipids or
proteins and 25% human plasma vol/vol. The protein concentration of this hydrophilic …