Neutrophil extracellular traps: A new link to cancer-associated thrombosis and potential implications for tumor progression
M Demers, DD Wagner - Oncoimmunology, 2013 - Taylor & Francis
M Demers, DD Wagner
Oncoimmunology, 2013•Taylor & FrancisCancers prime neutrophils to release extracellular DNA traps through the systemic release
of granulocyte colony-stimulating factor (G-CSF). We recently showed that these circulating
neutrophil extracellular traps (NETs) promote the establishment of a pro-thrombotic state.
The role of NETs in cancer biology and tumor progression may prove much more than an
unfortunate side effect of cancer.
of granulocyte colony-stimulating factor (G-CSF). We recently showed that these circulating
neutrophil extracellular traps (NETs) promote the establishment of a pro-thrombotic state.
The role of NETs in cancer biology and tumor progression may prove much more than an
unfortunate side effect of cancer.
Cancers prime neutrophils to release extracellular DNA traps through the systemic release of granulocyte colony-stimulating factor (G-CSF). We recently showed that these circulating neutrophil extracellular traps (NETs) promote the establishment of a pro-thrombotic state. The role of NETs in cancer biology and tumor progression may prove much more than an unfortunate side effect of cancer.
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