The microenvironment's role in mycosis fungoides and Sézary syndrome: from progression to therapeutic implications
A Pileri, A Guglielmo, V Grandi, SA Violetti, D Fanoni… - Cells, 2021 - mdpi.com
Cells, 2021•mdpi.com
Background: Mycosis fungoides (MF) and Sezary Syndrome (SS) are the most common
cutaneous T-cell lymphomas. It has been hypothesized that the interaction between the
immune system, cutaneous cells, and neoplastic elements may play a role in MF/SS
pathogenesis and progression. Methods: This paper aims to revise in a narrative way our
current knowledge of the microenvironment's role in MF/SS. Results and Conclusions:
Literature data support a possible implication of microenvironment cells in MF/SS …
cutaneous T-cell lymphomas. It has been hypothesized that the interaction between the
immune system, cutaneous cells, and neoplastic elements may play a role in MF/SS
pathogenesis and progression. Methods: This paper aims to revise in a narrative way our
current knowledge of the microenvironment's role in MF/SS. Results and Conclusions:
Literature data support a possible implication of microenvironment cells in MF/SS …
Background
Mycosis fungoides (MF) and Sezary Syndrome (SS) are the most common cutaneous T-cell lymphomas. It has been hypothesized that the interaction between the immune system, cutaneous cells, and neoplastic elements may play a role in MF/SS pathogenesis and progression. Methods
This paper aims to revise in a narrative way our current knowledge of the microenvironment’s role in MF/SS. Results and Conclusions
Literature data support a possible implication of microenvironment cells in MF/SS pathogenesis and progression, opening up new therapeutic avenues.
MDPI